BDBM25443 6-(3,4-difluorophenyl)-1-(pyridin-4-yl)-1,2,3,4-tetrahydronaphthalen-1-ol::Abiraterone mimetic, 6

SMILES OC1(CCCc2cc(ccc12)-c1ccc(F)c(F)c1)c1ccncc1

InChI Key InChIKey=ZKPQJJRSNGTTFM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25443   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

LigandPNGBDBM25443(6-(3,4-difluorophenyl)-1-(pyridin-4-yl)-1,2,3,4-te...)
Affinity DataIC50:  1.38E+4nMAssay Description:To measure CYP3A4 activity, the product of testosterone 6-hydroxylation, 6beta-hydroxytestosterone was determined. After incubation, the reaction was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed